The Harvey Lectures, Volume 2

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Academic Press, 1908 - Medicine
Includes list of members of the Harvey Society.
 

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Page 168 - ... organs become large, while the muscles waste away. Here, in time of affluence, the muscles store up nutritive material for the purpose of maintaining the life of the animal during starvation and of assisting in the function of reproduction. This instance seems to be quite a good illustration of the role which the factor of safety plays also in the function of the supply of the body with proteid food. The storing away of proteid, like the storing away of glycogen and fat, for the use in expected...
Page 67 - We have in this adaptation the most rational explanation of the meaning of the myriads of colon bacilli that inhabit the large intestine. This view is not inconsistent with the conception that under some conditions the colon bacilli multiply to such an extent as to prove harmful through the part they take in promoting fermentation and putrefaction.
Page 167 - Meltzer has formulated it independently on widely different grounds. " Of the supplies of energy to the animal we see that oxygen is luxuriously supplied. The supply of carbohydrates and fats is apparently large enough to keep up a steady luxurious surplus. . . . The liberal ingestion of proteid might be another instance of the principle of abundance ruling the structure and energies of the animal body. There is, however, a theory that in just this single instance the minimum is meant by nature to...
Page 168 - ... for the support of which there is not a single fact. On the contrary, some facts seem to indicate that Nature meant differently. Such facts are, for instance, the abundance of proteolytic enzymes in the digestive canal and the great capacity of the canal for absorption of proteids. Then there is the fact that proteid material is stored away for use in emergencies just as carbohydrates and fats are stored away. In starvation nitrogenous products continue to be eliminated in the urine which, according...
Page 66 - A long, largely anaerobic intestinal tract permitting gradual resorption of the contents is a physiologic necessity in order that a loss of water and its detrimental consequences may be spared the organism. The presence in the colon of immense numbers of obligate micro-organisms of the B. coli type may be an important defense of the organism in the sense that they hinder the development of that putrefactive decomposition which, if prolonged, is so injurious to the organism as a whole.
Page 19 - The antiseptic will not, as the unthoughtful assume, add its antibacterial power to the antibacterial power of the living organism. On the contrary, the antiseptic will directly antagonize the protective forces which the living organism has at command, it will paralyze the phagocytes, and will abolish the antibacterial power of the blood fluids. By the action of the antiseptic the disinfected surface will thus be left swept and garnished for reoccupation by the expropriated bacteria.
Page 21 - But probably there is at work here also another factor. A reduction in the antibacterial power of the blood may, as we shall see, supervene upon operative interference. 3. Treatment by the Determination of Lymph to the Focus of Infection. The method of extirpation by the knife is only one of the methods which can be employed for the treatment of bacterial infections when these have passed beyond the reach of antiseptic applications. Of the other methods the more important are the application of hot...
Page 91 - The Saccharo-Butyric Type of Chronic Excessive Intestinal Putrefaction. — In this type the seat of the putrefactive process is the large intestine and lower ileum. It is due to the activity of the strictly anaerobic butyric acid producing bacteria. Although our study is not yet exhausted it may confidently be stated that in many cases B.
Page 88 - ... is in general very slight and there are some older persons also who, even while suffering from disorders of digestion, do not form indol. On the other hand, the production of considerable quantities of indol in the large intestine is a feature of many instances of intestinal putrefaction and in some cases the quantity formed is large. That indol may be absorbed in considerable amounts is shown by the appearance of large quantities of indican in the urine of persons in whom the intestine contains...
Page 95 - Pasteurization or the ordinary boiling kills thfc lactic acid formers, but does not harm the spores of the putrefactive organisms. Cheese, except fresh home-made cheese, contains many putrefactive forms, and is best avoided, particularly inasmuch as many of these patients lack the protective action of the normal amount of hydrochloric acid in the stomach. 2. With rapid digestion and prompt absorption little pabulum for the putrefactive organisms reaches the colon. These processes are facilitated...

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